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Uniplar 1

Capsule - (1mcg)
arogga-brand
Unimed Unihealth Pharmaceuticals Ltd.
Generic: Paricalcitol
ā§ŗ 227.36
ā§ŗ 250
9% OFF

Medicine Overview of Uniplar 1 1mcg Capsule

āĻŦāĻžāĻ‚āĻ˛āĻž
English
Indication
Secondary hyperparathyroidism
Administration
May be taken with or without food.
Adult Dose
Oral Prevention & Treatment of Secondary Hyperparathyroidism Associated with Chronic Kidney Disease (Stage 3 & 4) PTH <500 pg/mL: 1 mcg PO qDay OR 2 mcg PO 3 times/week PTH >500 pg/mL: 2 mcg PO qDay OR 4 mcg PO 3 times/week Do not administer 3 times/week dosing no more frequently than every other day Titrate dose based on response. Monitoring parameters (Stage 3 & 4) Serum PTH at 2-4 week intervals PTH same or increased: Increase by 1 mcg/day OR 2 mcg three times/week PTH decreased <30%: Increase by 1 mcg/day OR 2 mcg three times/week PTH decreased >30%...
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Contraindication
Hypersensitivity, Hypercalcemia, hypervitaminosis D
Mode of Action
Synthetic vitamin D analog, reduces parathyroid hormone (PTH).
Precaution
Monitor serum calcium and phosphorus frequently; reduce dose or stop the drug if calcium (in mg/dL) times phosphorus (in mg/dL) product >75 Patients receiving digitalis; digitalis toxicity is potentiated by hypercalcemia Strong CYP3A4 inhibitors may increase paricalcitol AUC. May increase serum creatinine in pre-dialysis patients. Hepatic impairment Lactation: not known if distributed into breast milk, use caution
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Side Effect
>10% Nausea (13%) 1-10% Vomiting,Edema,Palpitation,Chills,Pneumonia,Lightheadedness,GI bleeding,Flu,Sepsis,Hypokalemia,Hypercalcemia,Increase in blood creatinine
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Interaction
Digitalis; ketoconazole & other strong P450 3A inhibitors including atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, voriconazole. May interfere absorption w/ cholestyramine (cap only). Increased risk of hypercalcemia w/ prescription-based phosphate or vit D-related medicinal products & Ca-containing prep or thiazide diuretics. Mg- & Al-containing prep (eg, antacids, phosphate-binders).
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āĻŦā§āĻ¯āĻŦāĻ¸āĻžāĻ° āĻœāĻ¨ā§āĻ¯ āĻĒāĻžāĻ‡āĻ•āĻžāĻ°āĻŋ āĻĻāĻžāĻŽā§‡ āĻĒāĻŖā§āĻ¯ āĻ•āĻŋāĻ¨āĻ¤ā§‡ āĻ°ā§‡āĻœāĻŋāĻ¸ā§āĻŸā§‡āĻļāĻ¨ āĻ•āĻ°ā§āĻ¨
Register
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Uniplar 1

Capsule - (1mcg)
arogga-brand
Unimed Unihealth Pharmaceuticals Ltd.
Generic: Paricalcitol
ā§ŗ 227.36
ā§ŗ 250
9% OFF
Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.