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Opsonin Pharma Limited
Generic: Metoclopramide Hydrochloride
৳ 14.42
৳ 15.87
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বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Metocol 100 ml.
SAFE IF PRESCRIBED
Metocol 100 ml is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
CONSULT YOUR DOCTOR
Metocol 100 ml is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Metocol 100 ml may cause side effects which could affect your ability to drive.
Metocol 100 ml may cause drowsiness, dizziness, dyskinesia and dystonias which could affect the vision and may interfere with the ability to drive.
CAUTION
Metocol 100 ml should be used with caution in patients with kidney disease. Dose adjustment of Metocol 100 ml may be needed. Please consult your doctor.
SAFE IF PRESCRIBED
Metocol 100 ml is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Metocol 100 ml may not be needed in these patients. Please consult your doctor.
Medicine Overview of Metocol 100 ml 5mg/5ml Syrup
Introduction
Metocol 100 ml is a prescription medicine used to treat nausea, vomiting, and prevent the feeling of fullness during or shortly after a meal. It also treats stomach discomfort, or heartburn caused by the flow of the stomach contents back into your food pipe. Metocol 100 ml is taken before meals preferably at bedtime in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should take this medicine until your doctor tells you to stop. Let your doctor know about all other...
... Show moreUses of Metocol 100 ml
- Nausea
- Vomiting
- Indigestion
Side effects of Metocol 100 ml
Common
- Restlessness
- Sleepiness
- Fatigue
How to use Metocol 100 ml
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metocol 100 ml is to be taken empty stomach.
How Metocol 100 ml works
Metocol 100 ml is a prokinetic. It works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach.
What if you forget to take Metocol 100 ml?
If you miss a dose of Metocol 100 ml, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Metocol 100 ml helps relieve nausea and vomiting.
- It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
- Avoid consuming alcohol when taking Metocol 100 ml as it may cause excessive drowsiness.
- Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
Brief Description
Indication
Gastro-oesophageal reflux disease, Diabetic gastric stasis, Nausea and vomiting associated w/ cancer chemotherapy or radiotherapy, Postoperative nausea and vomiting
Administration
Should be taken on an empty stomach. Take ½ hr before meals.
IV Administration
NS is preferred diluent because drug is most stable in this solution
Dose <10 mg: IV push over 1-2 minutes
Dose >10 mg: Dilute in 50 mL D5W or NS, and infuse over at least 15 minutes
... Show moreAdult Dose
Oral Diabetic gastric stasis Adult: 10 mg 4 times daily for 2-8 wk. Nausea and vomiting associated with cancer chemotherapy or radiotherapy Adult: 10 mg, up to tid. Max duration: 5 days. Gastro-oesophageal reflux disease Adult: 10-15 mg 4 times daily, depending on severity of symptoms. If symptoms are intermittent, may give single doses of 20 mg prior to provoking situation. Max duration: 12 wk. Elderly: 5 mg/dose. Parenteral Diabetic gastric stasis Adult: 10 mg 4 times daily by IM inj or slow IV inj over 1-2 min for up to 10 days. Convert to oral admin when symptoms subside...
... Show moreChild Dose
Small Bowel Intubation/Radiologic Examination of Upper GI Tract <6 years old: 0.1 mg/kg IV over 1-2 minutes 6-14 years old: 2.5-5 mg IV over 1-2 minutes >14 years old: 10 mg IV over 1-2 minutes Gastroesophageal Reflux Disease Neonate: 0.15 mg/kg IV q6hr Infant: 0.1 mg/kg IV/IM/PO q6-8hr 30 minutes before meals and at bedtime Not to exceed 0.3-0.75 mg/kg/day Diabetic Gastroparesis <6 years old: 0.1 mg/kg PO q8hr; not to exceed 0.1 mg/kg >6 years old: 0.5 mg/kg/day PO divided q8hr Postoperative Nausea & Vomiting 0.1-2 mg/kg IV q6-8hr PRN Chemotherapy-Induced Nausea & Vomiting 1-2 mg/kg IV (infused over...
... Show moreRenal Dose
Renal impairment: CrCl <40 mL/min, decrease dose by 50%; CrCl <10 mL/min, decrease dose by 75%
... Show moreContraindication
GI haemorrhage, mechanical obstruction or GI perforation; confirmed or suspected pheochromocytoma; history of neuroleptic or metoclopramide-induced tardive dyskinesia; epilepsy, Parkinson's disease; history of methaemoglobinaemia w/ metoclopramide or of NADH cytochrome-b5 deficiency. Concomitant use w/ levodopa or dopaminergic agonists.
Mode of Action
Metoclopramide enhances the motility of the upper GI tract and increases gastric emptying without affecting gastric, biliary or pancreatic secretions. It increases duodenal peristalsis which decreases intestinal transit time, and increases lower oesophageal sphincter tone. It is also a potent central dopamine-receptor antagonist and may also have serotonin-receptor (5-HT3) antagonist properties.
Precaution
Patients w/ underlying neurological conditions, cardiac conduction disturbances, uncorrected electrolyte imbalance, bradycardia. Children, elderly. Renal or hepatic impairment, porphyria, epilepsy, Parkinson's disease, history of depression. Ability to drive or operate machineries may be impaired. Pregnancy and lactation. Monitor patients on prolonged therapy. Increased risk of tardive dyskinesia in patients on prolonged or high-dose treatment.
Lactation: Drug crosses into breast milk; use caution; concern may be warranted according to American Academy of Pediatrics
... Show moreSide Effect
>10%
Extrapyramidal symptoms (dystonic reactions in 25% of young adults 18-30 years old)
1-10%
Fatigue (2-10%),Restlessness (10%),Sedation (10%),Headache (4-5%),Dizziness (1-4%),Somnolence (2-3%)
Frequency Not Defined
Diarrhea,Nausea,Galactorrhea,Gynecomastia,Impotence,Menstrual disorders,Neuroleptic malignant syndrome,Hematologic abnormalities
Potentially Fatal: Neuroleptic malignant syndrome; cardiac conduction disorders may occur with IV dosage form.
... Show moreInteraction
Increased sedative effects with CNS depressants. GI effects antagonised by antimuscarinics and opioids. Reduces absorption of digoxin. Increases absorption of ciclosporin, levodopa, aspirin, paracetamol. Interferes with hypoprolactinaemic effect of bromocriptine. Inhibits serum cholinesterase and prolongs neuromuscular blockade produced by suxamethonium and mivacurium.
Potentially Fatal: Serotonin syndrome with sertraline (SSRI).
... Show moreব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
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Opsonin Pharma Limited
Generic: Metoclopramide Hydrochloride
৳ 14.42
৳ 15.87
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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.